Super Avana is a time-tested and approved drug that can produce the necessary effects. Containing Avanafil and Dapoxetine, as active components, the treatment allows a man to have a successful sexual intercourse with a stiff and durable erection and timely ejaculation. Belonging to a class of PDE-5 inhibitors, Super Avana stimulates and improves the blood circulation and other body functions inevitable for healthy sex. However, in this article we will see what dapoxetine is and how it works in a patient’s organism.
What Is Dapoxetine?
Dapoxetine is an innovative and quite potent serotonin transport inhibitor which has a unique pharmacokinetic profile and pharmacological characteristics that allow its quick distribution in the patient’s body and differ from other pharmacokinetics present in conventional selective serotonin reuptake inhibitors. Dapoxetine is a fast-acting ingredient, and it is presently further researched and successfully used in premature ejaculation treatment. Its peak concentration in the plasma is observed in 1.5 hour after the intake, and this is faster than other similar compounds. After the administration, Dapoxetine is absorbed quite fast, and the absorption is followed by quick decline in plasma concentration. These unique properties make it a perfect ingredient for PE medications.
Mechanism of Action
Dapoxetine is responsible for another important sexual function – ejaculation. It is a selective serotonin reuptake inhibitor that increases serotonin activity in the central nervous system. Being an important neurotransmitter, serotonin is involved in passing of the message between the nerve cells. Boosting the action of serotonin in the central nervous system helps prolong the time necessary for ejaculation.
Due to its formula and properties, it delays the ejaculation reflex and extends the intravaginal ejaculatory latency time (IELT). Among other SSRIs Dapoxetine is reported to be a unique compound, which is absorbed fast, metabolized rapidly and is not halogenated. It is completely eliminated from the organism within 24 hours and reports minimal accumulation in the blood after daily dose administration. During clinical studies Dapoxetine effectiveness was tested in men with different premature ejaculation conditions. Due to the fast concentration of the compound, patients were obliged to take different doses of Dapoxetine from one to three hours before a presumable sexual contact. As a result, when taken on-demand, it increased the IELT by several times. In the light of such results the researchers concluded that Dapoxetine was the only PE medication that showed effectiveness after the first intake, if administered from one to three hours before a sexual intercourse.